The International Cosmetic Peptide Working Group (ICPEWG) released a revised technical note in Q2 2025 clarifying how suppliers should report related peptides, deletion sequences, and racemization markers on Certificates of Analysis for INCI-listed materials. Importers serving the EU and UK markets are already referencing the document in raw-material qualification questionnaires.

Key takeaway for buyers: impurity thresholds should be negotiated per sequence and per intended use level, not accepted as generic boilerplate. Suppliers unable to provide LC-MS peak assignment for flagged minor components face longer onboarding cycles.